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亲属活体供肾移植治疗Alport综合征(附1例报道并文献复习)
引用本文:王海灏,张伟杰,何晓峰,曾凡军,郭晖,吕永曼. 亲属活体供肾移植治疗Alport综合征(附1例报道并文献复习)[J]. 临床泌尿外科杂志, 2006, 21(5): 369-371
作者姓名:王海灏  张伟杰  何晓峰  曾凡军  郭晖  吕永曼
作者单位:华中科技大学同济医学院附属同济医院器官移植研究所,武汉,430030;华中科技大学同济医学院附属同济医院肾病内科
摘    要:目的:探讨亲属活体供肾移植治疗Alport综合征(AS)的安全性和治疗特点。方法:2004年7月为1例Alport综合征患者施行亲属活体供肾移植手术,术后对供、受者均随访1年7个月,分析亲属供肾移植治疗AS的特点以及评价活体供肾的安全性。结果:供者各项生命指标良好,肝肾功能无明显变化;受者术后肾功能恢复理想,随访期间未见AS复发及其他脏器功能的继续损害。结论:Alport综合征是一种临床上较少见的遗传性疾病。亲属活体供肾移植治疗AS是一种可供移植医生考虑的治疗手段,对于是否存在术后的AS复发尚有待更长期的临床观察。

关 键 词:Alport综合征  活体供肾  肾移植
文章编号:1001-1420(2006)05-0369-03
收稿时间:2005-08-15
修稿时间:2005-08-15

Living related donor kidney transplantation for Alport Syndrome
WANG Haihao,ZHANG Weijie,HE Xiaofeng,ZENG Fanjun,GUO Hui,YU Yongman. Living related donor kidney transplantation for Alport Syndrome[J]. Journal of Clinical Urology, 2006, 21(5): 369-371
Authors:WANG Haihao  ZHANG Weijie  HE Xiaofeng  ZENG Fanjun  GUO Hui  YU Yongman
Affiliation:1Institute of Organ Transplantation, 2Nephrosis Department, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China
Abstract:Objective:To summarize the clinical experience of treating Alport Syndrome by living related donor kidney transplantation.Methods:A patient with AS was managed by living related donor kidney transplantation in July 2004.Results:No death and serious complications occurred in the donor after operation. 19 months follow-up revealed that the recipient recovered rapidly after operation and had normal kidney function.Conclusions:Living related donor kidney transplantation may be an effective and safe treatment for AS, but need time to confirm it.
Keywords:Alport Syndrome  Living related donors  Kidney transplantation
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