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Black-white differences in plasma lipids and lipoproteins in adults: the Cincinnati Lipid Research Clinic population study.
Authors:J A Morrison  I deGroot  K A Kelly  M J Mellies  P Khoury  B K Edwards  D Lewis  A Lewis  M Fiorelli  G Heiss  H A Tyroler  C J Glueck
Affiliation:1. The Lipid Research Clinic and General Clinical Research Center, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 USA;2. The School of Public Health, University of North Carolina, College of Medicine, Chapel Hill, North Carolina 27514 USA
Abstract:
Black—white lipoprotein differences were studied in 43 pairs of adult males and 51 pairs of adult females to test the hypothesis that in a heterogeneous suburban biethnic setting, blacks have higher levels of high density lipoprotein cholesterol (C-HDL), lower levels of low density lipoprotein cholesterol (C-LDL), and lower levels of triglyceride (TG) when pair-matched by total plasma cholesterol, age, and sex with whites. With essentially identical total plasma cholesterol levels and comparable degrees of ponderosity, black males had lower plasma TG (P < 0.05) and higher plasma C-HDL levels (P < 0.005). There were no significant male black—white differences in C-LDL, but the ratio of C-LDL to C-HDL was lower in black males (P < 0.01). There were no significant differences in any lipoprotein fractions or the C-LDL/C-HDL ratio between black and white females, although black females had slightly lower plasma TG and slightly higher C-HDL than white females.
Keywords:Address reprint requests to Charles J. Glueck   M.D.   General Clinical Research Center   Cincinnati General Hospital   234 Goodman Street C2-3   Cincinnati   Ohio 45267.
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