| 膜分离技术制备的热毒净颗粒药理作用研究 |
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| 引用本文： | 胡小鹰,郭立玮,陈汝炎,朱萱萱. 膜分离技术制备的热毒净颗粒药理作用研究[J]. 南京中医药大学学报, 2002, 18(5): 280-282 |
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| 作者姓名： | 胡小鹰 郭立玮 陈汝炎 朱萱萱 |
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| 作者单位： | 1. 南京中医药大学植物药研究与新药开发中心
2. 南京中医药大学附属医院,江苏,南京,210029 |
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| 基金项目： | 国家中医药管理局重点项目 (97Z0 2 3 ) |
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| 摘 要： | 目的 探讨热毒净颗粒的药理作用。方法 观察热毒净颗粒对感染金黄色葡萄球菌小鼠存活率的影响 ,对感染流感病毒小鼠肺指数的影响及对大肠杆菌内毒素致发热家兔体温的影响。结果 热毒净颗粒可明显提高感染金黄色葡萄球菌小鼠的存活率 (P <0 .0 5 ) ,明显降低感染流感病毒小鼠的肺指数 (P <0 .0 1)和大肠杆菌内毒素致发热家兔的体温 (P<0 .0 5～ 0 .0 1)。结论 采用膜分离技术制备的热毒净颗粒具有抗菌、抗病毒及退热作用。
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| 关 键 词： | 热毒净颗粒 脱分离技术 抗菌作用 抗病毒作用 退热作用 中药 药理 |
| 文章编号： | 1000-5005(2002)05-0280-03 |
| 修稿时间： | 2002-05-06 |
Pharmacological Effect of Membrane Separation Technique Used in Preparing Redujing Granule |
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| HU Xiao ying ,GUO Li wei ,CHEN Ru yan ,ZHU Xuan xuan. Pharmacological Effect of Membrane Separation Technique Used in Preparing Redujing Granule[J]. Journal of Nanjing University of Traditional Chinese Medicine(Natural Science), 2002, 18(5): 280-282 |
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| Authors: | HU Xiao ying GUO Li wei CHEN Ru yan ZHU Xuan xuan |
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| Affiliation: | HU Xiao ying 1,GUO Li wei 1,CHEN Ru yan 1,ZHU Xuan xuan 2 |
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| Abstract: | OBJECTIVE To explore into the pharmacological effect of Redujing Granule. METHOD The effect of Redujing Granule on the survival rate of mice infected with staphylococcus aureus, on the pulmonary indexes of rats infected with influenza viruses and on the body temperature of rabbits with fever caused by colitoxin was observed. RESULT Redujing Granule could markedly increase the survival rate of mice infected with staphylococcus aureus and markedly reduce the pulmonary indexes of rats infected with influenza viruses and the body temperature of rabbits with fever caused by colitoxin. CONCLUSION Redujing Granule prepared with the membrane separation technique has anti-bacterial, anti-viral and antipyretic effect. |
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| Keywords: | Redujing Granule membrane separation technique anti-bacterial effect anti-viral effect antipyretic effect |
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