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| 真菌毒素雪腐镰刀菌烯醇对培养软骨细胞影响的超微结构观察 | |
| 引用本文： | 曹峻岭 熊咏民. 真菌毒素雪腐镰刀菌烯醇对培养软骨细胞影响的超微结构观察[J]. 中国地方病学杂志, 1995, 14(6): 360-362 |
| 作者姓名： | 曹峻岭 熊咏民 |
| 作者单位： | 西安医科大学地方性骨病研究所 |
| 摘 要： | 采用软骨细胞体外单层培养的方法，观察真菌毒素ＮＩＶ对幼兔关节软骨细胞超微结构的作用。结果表明ＮＩＶ对软骨细胞膜系统和细胞浆具有明显的损伤作用，特别是对培养早期的软骨细胞具致命的损伤，以后其损伤程度随毒素浓度的升高而加重。ＮＩＶ与大骨节病的关系有待进一步探讨。 |
| 关 键 词： | 真菌毒素，雪腐镰刀菌烯醇（NIV），培养软骨细胞，大骨节病 |
Effect of Nivalenol (NIV) on Ultrastructure of cultured chondrocytes |
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| Cao Junling, Xiong Yongmin, Zhang Shiyuan, Mo Dongxu. Effect of Nivalenol (NIV) on Ultrastructure of cultured chondrocytes[J]. Chinese Jouranl of Endemiology, 1995, 14(6): 360-362 | |
| Authors: | Cao Junling Xiong Yongmin Zhang Shiyuan Mo Dongxu |
| Abstract: | The effect of NIV on the ultrastructure of rabbit articula chondrocytes was observed by using the monolayer cultured chondrocytes in vitro. The result showed that the membrane and subcellular organelles of the chondrocytes were damaged markedly,particularly in earlier cultured chondrocytes. The severity of damage was increased with the concentration of toxin in the media. The relationship between NIV and Kashin-Beck Disease needs to be further studied. |
| Keywords: | mycotoxin nivalenol (NIV) cultured chondrocyte Kashin-Beck Disease(KBD) |
| 本文献已被 CNKI 维普 等数据库收录！ | |