2型糖尿病患者糖化血红蛋白与尿酸检测的临床意义

目的探讨2型糖尿病患者糖化血红蛋白与尿酸检测的临床意义。方法选择该院2009年1月—2011年6月2型糖尿病患者33例（24h尿微量白蛋白排泄率≥300mg）作为观察I组,33例2型糖尿病患者（24h尿微量白蛋白排泄率30～299mg）作为观察II组,同期33例身体健康体检者作为对照组,观察比较3组患者空腹血糖（FPG）、糖化血红蛋白（HbA1c）、尿酸（UA）、血肌酐的变化情况。结果观察组I组与观察II组的HbA1c、UA均显著高于对照组,观察I组的HbA1c、UA高于观察II组,两组比较,差异有统计学意义（P〈0.05）。结论糖化血红蛋白、尿酸检测对2型糖尿病患者肾损害程度的病情预测和诊治具有重要意义。

Clinical significance of detecting serum levels of glycosylated hemoglobin and uric acid in patients with type 2 diabetes mellitus

Objective To explore the clinical value of detecting the serum levels of glycosylated hemoglobin and uricacid in patients with type 2 diabetes mellitus.Methods 33 patients with diabetes mellitu and urinary albumin excretion ≥300mg in 24 h were served as observation group I,33 patients with diabetes mellitus and urinary albumin excretion between 30mg and 299mg served as observation group II,and 33 healthy individuals were selected as control group.Fasting blood glucose,HbA1c,UA,and Cr of the three groups were determined,and the results were compared among them.Results The levels of HbA1c and UA in observation groups I and II were higher than those of the control group.The levels of HbA1c and UA in the observation group I were higher than those in the observation group II,and the difference was statistically significant(P<0.05).Conclusion Detection of HbA1c and UA has an important significance for prediction of renal impairment and its diagnosis and treatment in patients with type 2 diabetes mellitus.