Muscle |
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Affiliation: | 1. Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden;2. Division of Cardiovascular Diseases, College of Medicine, Mayo Clinic, Rochester, Minnesota;3. Allegheny General Hospital, Pittsburgh, Pennsylvania;4. NT&D Research, Medtronic, Minneapolis, Minnesota;5. Division of Cardiovascular Diseases, Department of Medicine, University of Alabama, Birmingham, Alabama |
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Abstract: | Two important types of muscle are skeletal and smooth muscle. Their similarities and differences are described with regard to general morphology and ultrastructure (arrangement of filaments and T tubules), linking structure to physiological functions. The sliding-filament theory of muscle contraction is explained. Finally, the processes by which nerves excite muscle contraction (excitation–contraction coupling) are outlined, again relating variations in these processes in the two types of muscle to differences between them in their role in the body. |
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Keywords: | Actin calcium contractile filaments myosin sarcolemma sarcomere sarcoplasm T tubules tropomyosin |
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