Delayed exstrophy repair (DER) does not compromise initial bladder development |
| |
Affiliation: | 1. Department of Paediatric Urology, Royal Manchester Children''s Hospital, Oxford Road, Manchester M13 9WL, UK;2. Department of Paediatric Anaesthesia, Royal Manchester Children''s Hospital, Manchester, UK;3. Department of Paediatric Orthopaedic, Royal Manchester Children''s Hospital, Manchester, UK;1. Department of Pediatric Surgery, Trakya University, Faculty of Medicine, 22030 Edirne, Turkey;2. Department of Histology and Embryology, Faculty of Medicine, Trakya University, 22030 Edirne, Turkey;3. Department of Bioengineering (Biochemistry Division), Faculty of Chem. and Met. Eng., Yıldız Technical University, Istanbul, Turkey |
| |
Abstract: | ObjectiveDelayed exstrophy repair (DER) represents an alternative to early neonatal bladder closure. This study aims to define the consequence of DER on bladder growth in bladder exstrophy patients who underwent routine DER, compared with those who underwent immediate postnatal reconstruction.MethodsBetween 2000 and 2005, classic bladder exstrophy patients referred to the authors' institution underwent early neonatal bladder closure (group 1). Subsequently, classic bladder exstrophy patients referred to the authors' institution were treated with an elective DER (group 2). Bladder capacity was assessed between the age of 1 and 4 years with an unconscious cystogram. When dilating VUR was present, the volume of the contrast migrated into the ureter was calculated and subtracted.ResultsSixty patients were treated between 2000 and 2012. Complete follow-up data were available for 45 patients and they were included in the study: 21 in group 1 (11 males) and 24 in group 2 (14 males). The mean (SD) bladder volumes were 72.85 (28.5) ml in group 1 and 72.87 (34.9) in group 2 (p = 0.99).ConclusionIn the authors' experience, DER does not reduce the subsequent bladder capacities compared with neonatal exstrophy closure. |
| |
Keywords: | Bladder exstrophy Bladder growth Delayed repair |
本文献已被 ScienceDirect 等数据库收录! |
|