碳酰胺过氧化氢在鼻咽癌放疗增敏中的应用

【目的】探讨碳酰胺过氧化氢对增强鼻咽癌放射治疗敏感性的应用价值。【方法】80例鼻咽癌患者随机分为对照组（单纯放疗）、试验组（放疗＋碳酰胺过氧化氢），比较两组疗效和放射性损伤程度。【结果】试验组完全缓解率、一年生存率、一年无瘤生存率均高于对照组，差异显著。两组患者在放射性损伤程度方面相比较均无显著性差异。【结论】碳酰胺过氧化氢可提高鼻咽癌放射治疗敏感性，且不增加毒副反应。

Effect of Carbamide Peroxide as Radiosensitizer in the Treatment of Nasopharyngeal Carcinoma

Objective] To investigate the value of carbamide peroxide for the treatment for nasopharyngeal carcinoma. Methods]Eighty patients with nasopharyngeal carcinoma were randomly divided into two groups. The control group received radiotherapy and the experimental group received radiotherapy plus carbamide peroxide. The clinical efficacy and radiation injury were compared in two groups. Results] Complete remission rate and one-year survival rate in experimental group were significantly higher than those in control group. There was no significant difference in radiation injury between two groups. Conclusion] Carbamide peroxide Can improve the clinical efficacy of radiotherapy without increasing radiation side effects.