克罗恩病内科治疗与营养支持的作用

克罗恩病（CD）是一种病因未明的慢性肉芽肿性炎症性肠病，在我国发病率有明显上升趋势。该病迄今尚无彻底治愈方法。传统的药物治疗存在很大局限性，生物制剂的问世给CD患者带来了新的治疗选择，也引发了关于“上阶梯”和“下阶梯”治疗策略的争论。合理的营养支持在CD的综合治疗中占有重要地位。本文主要对CD传统药物的疗效、药物治疗的新进展、营养支持的作用和现状以及CD新的治疗策略进行评述。

Crohn's disease: medical treatment and role of nutritional support

Crohn's disease (CD) is a chronic granulomatous disease with unknown causes, and its incidence shows a rising trend in China. So far there is no way for the complete cure of the disease. Conventional drug therapy has many limitations. The appearance of biological agents brings new treatment options for CD and also initiates a debate over "Step-up" versus "Top-down" strategies. Rational nutrition supplement plays an important role in the comprehensive treatment of CD. This paper reviews the efficacy of conventional drugs, new progress in drug therapy, roles and status of nutritional support, and new treatment strategies for CD.