治疗2型糖尿病3种方案的成本-效果分析

目的：比较3种用药方案治疗2型糖尿病的疗效与成本,为临床合理用药提供依据。方法：回顾性分析86例2型糖尿病患者3种治疗方案（A组：二甲双胍片1.0～1.5g·d~（-1）;B组：精蛋白生物合成人胰岛素30R注射液5～64u,早、晚餐前30minn ih;C组：二甲双胍片1.0～1.5g·d~（-1）＋精蛋白生物合成人胰岛素30R注射液5～64u,早、晚餐前30mim ih）,进行成本-效果比较。结果：A、B、C3组出院时血糖平均值差异无统计学意义（P〉0.05）,3组的血糖下降百分率分别为15.04%、17.96%、26.95%,C组与A、B组差异有统计学意义（P〈0.05）,A组与B、C组总成本的差异有统计学意义（p〈0.05）,A、B、C3组的总成本-效果比分别为65.63、69.66、48.46。B、C组相对于A组的增量总成本-效果比分别为90.41和26.77。结论：二甲双胍与精蛋白生物合成人胰岛素30R联合用药是2型糖尿病患者住院治疗成本效果较好的方案。

Cost-effectiveness Analysis of Three Kinds of Treatment on Type 2 Diabetes

Objective:To compare the three kinds of different options for treatment of type 2 diabetic patients,to provide refevence for clinical medicine.Methods:86 patients were assigned into three groups according to them received, the three kinds of treatment(A group:metformin;B Group:protamine biosynthesis of human insulin-30R;C Group:protamine biosynthesis of human insulin-30R+metformin).Results:The average blood sugar to leave hospital groups of the three had no significant differences(P>0.05 ),the percentage of blood glucose decreased of three groups,were respectively 15.04%、17.96%and 26.95%.A and C group、B and C group had significant differenees(P<0.05).In the three groups,the average blood glucose decreased by one percentage point,A group,B group and C group were 65.63 yuan, 69.66 yuan and 48.46 yuan.B and C group relative to the A group of incremental cost-effectiveness ratio were 90.41, 26.77.Conclusion:C group is a good cost-effectiveness scheme for treatment of type 2 diabetie patients by hospitalization.