China-PAR模型与Framingham危险评分对中国绝经后女性健康体检人群心血管疾病风险评估的比较研究

目的:比较美国Framingham危险评分(FRS)和中国动脉粥样硬化性心血管疾病风险预测模型(China-PAR)对中国绝经后女性健康体检人群10年心血管疾病(CVD)发病风险评估的差异,以期找到可更加准确地评估该人群10年CVD发病风险的方法.方法:回顾性选取进行健康体检的绝经后女性4100例,对所有研究对象进行问...

A comparative study of China-PAR model and Framingham risk score on cardiovascular disease risk assessment in Chinese postmenopausal women

Objective:To compare the difference between Framingham risk score(FRS)and Chinese atherosclerotic cardiovascular disease risk prediction model(China-PAR)in the risk assessment of 10-year cardiovascular disease(CVD)in Chinese postmenopausal women,so as to find a more accurate method to assess the risk of CVD in this population.Methods:A total of 4100 postmenopausal women who underwent physical examination were retrospectively selected.All the subjects were investigated by questionnaire,physical examination,and serological test.FRS and China-PAR model were used to predict the risk of CVD in all the subjects in the next 10 years.Results:(1)The mean value of CVD absolute risk predicted by China-PAR model and FRS was 7.2%and 9.9%,respectively.There were significant differences in mean value and low-risk ratio between the two methods(all P<0.05).(2)There was significant difference between the two methods in predicting the three risk assessment results of low,medium,and high risk in different age groups(all P<0.05),and the results of risk level of different age groups were the same.(3)The consistency of the two methods was poor,and Kappa=0.139<0.40(P<0.05).Conclusion:The average risk and high-risk ratio of CVD in Chinese postmenopausal women health examination population predicted by China-PAR model in the next 10 years are lower than those predicted by FRS in the United States.The prediction results of these two methods have poor consistency,and China-PAR may be more suitable for Chinese postmenopausal women with physical examination.