三维斑点追踪技术评价2型糖尿病合并高尿酸血症患者左室整体收缩功能

目的 探讨三维斑点追踪(3D-STI)技术评价2型糖尿病(T2DM)合并高尿酸血症(HU)患者左室整体收缩功能的临床价值.方法 选取62例T2DM患者,根据是否合并HU分为单纯T2DM组33例和T2DM+HU组29例,另选健康体检者40例为对照组,各组均行常规和三维超声心动图检测,应用3D-STI分析软件获取并比较各组...

Evaluation of left ventricular global systolic function in patients with type 2 diabetes mellitus complicated with hyperuricemia by three-dimensional speckle tracking imaging

Objective To analyze the left ventricular global systolic function with three-dimensional speckle tracking imaging(3D-STI)in patients with type 2 diabetes mellitus(T2DM)complicated with hyperuricemia(HU).Methods Sixty-two patients with T2DM were divided into T2DM group(33 cases)and T2DM+HU group(29 cases)according to whether they had HU,and 40 healthy subjects were selected as the control group.All groups were examined by routine and three-dimensional echocardiography.The 3D-STI analysis software was used to obtain and compare the differences in 3D-STI parameters between the groups,and the influencing factors were analyzed.Results Left ventricular global longitudinal strain(GLS)in T2DM group was lower than that in control group,and the difference was statistically significant(P<0.05).There were no significant difference in left ventricular global circumscribed strain(GCS),area strain(GAS),and radial strain(GRS)between the T2DM group and control group.GLS,GAS,GCS and GRS in T2DM+HU group were lower than those in control group and T2DM group,and the differences were statistically significant(all P<0.05).Fasting blood glucose and serum uric acid were independent influencing factors of left ventricular global strain values in all directions.Conclusion 3D-STI can sensitively detect the impaired left ventricular global systolic function in patients with T2DM complicated with HU at early stage,providing a reliable basis for clinical practice.