紫杉醇药物涂层球囊治疗冠状动脉支架内再狭窄的效果及近期预后观察

目的 探讨紫杉醇药物涂层球囊(DCB)治疗冠状动脉支架内再狭窄(ISR)的效果及近期预后.方法 选取2016年5月—2019年6月收治的冠心病行经皮冠状动脉介入(PCI)术后ISR患者70例,根据治疗方法的不同分为观察组36例和对照组34例,观察组采用DCB治疗,对照组采用药物涂层支架(DES)治疗.比较两组再次PCI...

Efficacy and Short-term Prognosis of Paclitaxel Drug-coated Balloon in Treatment of In-Stent Restenosis

Objective To investigate efficacy and short-term prognosis of Paclitaxel drug-coated balloon(DCB)in treatment of in-stent restenosis(ISR).Methods A total of 70 patients with ISR undergoing percutaneous coronary intervention(PCI)during May 2016 and June 2019 were divided into observation group(n=36)and control group(n=34)according to different treatment methods.Observation group was treated with DCB,while control group was treated with drug-eluting stent(DES).Diameters and stenosis rate of target lesion lumen before,immediately and in the 6 th months after PCI were compared between two groups.The treatment related expenses during hospitalization,incidence rate of major adverse cardiovascular events(MACE)in the 6 th after PCI,and recurrence rates of ISR in the 12 th months after PCI were compared between two groups.Results values of lumen diameter of target lesion and lumen stenosis rate of target lesion were significantly improved immediately and in the 6 th months after operation in two groups,and the values in observation group were better than those in control group(P<0.01).There were no significant differences in the total expenses of hospitalization,average daily expenses and consumables expenses between two groups(P>0.05).The total incidence rate of MACE and incidence rate of ISR after operation in the observation group were significantly lower than those in control group(P<0.05).Conclusion DCB in treatment of ISR may obtain better benefit immediately and maintain a good short-term effect after operation without increasing economic burden,and it may also reduce incidence rate of MACE and recurrence rate of ISR.