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胃肠外营养中氨基酸摄入量与极低出生体重儿胃肠外营养相关性胆汁淤积的关系分析
引用本文:蒋晓梅. 胃肠外营养中氨基酸摄入量与极低出生体重儿胃肠外营养相关性胆汁淤积的关系分析[J]. 中国医药导报, 2011, 8(35): 38-40
作者姓名:蒋晓梅
作者单位:广西壮族自治区来宾市人民医院新生儿科,广西来宾,546100
摘    要:目的:探讨胃肠外营养(PN)中氨基酸摄入量与PN相关性胆汁淤积的关系,为减少和避免PN相关性胆汁淤积的发生提供依据。方法:对2005年12月~2008年5月低氨基酸组(采用PN方案)43例和2008年6月~2010年12月高氨基酸组(极低出生体重儿)39例的新生儿临床资料进行回顾性分析,比较两组PN相关性胆汁淤积发病率的差异。结果:低氨基酸组患儿氨基酸摄入量[(35.6±15.7)g/kg]小于高氨基酸组[(47.4±19.0)g/kg](P〈0.01);高氨基酸组患儿PN相关性胆汁淤积的发生率为41.0%,高于低氨基酸组[(18.6%)](P〈0.05)。结论:在接受PN的极低出生体重儿中,摄入高剂量的氨基酸易发生PN相关性胆汁淤积,推荐采用低氨基酸PN方案。

关 键 词:极低出生体重儿  胃肠外营养  氨基酸  胃肠外营养相关性胆汁淤积

Analysis of relationship between different amino acid intake on parenteral nutrition and the incidence of parenteral nutrition-associated cholestasis in very low birth weight infants
JIANG Xiaomei. Analysis of relationship between different amino acid intake on parenteral nutrition and the incidence of parenteral nutrition-associated cholestasis in very low birth weight infants[J]. China Medical Herald, 2011, 8(35): 38-40
Authors:JIANG Xiaomei
Affiliation:JIANG Xiaomei Department of Neonatology,the People's Hospital of Laibin City,Guangxi Zhuang Autonomous Region,Laibin 546100,China
Abstract:Objective: To analyze the relationship between different amino acid intake on parenteral nutrition(PN) and the incidence of parenteral nutrition-associated cholestasis in very low birth weight infants.Methods: 43 cases in low amino acid group hospitalized from December 2005 to May 2008 and 39 cases in high amino acid group hospitalized from June 2008 to December 2010,the data of the two groups were retrospectively analyzed and the incidence of PN associated cholestasis were compared.Results: Amino acids int...
Keywords:Very low birth weight infant  Parenteral nutrition  Amino acid  Parenteral nutrition-associated cholestasis  
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