碎裂QRS波群在心脏再同步化治疗中的研究进展

心力衰竭是21世纪最严重的心血管问题,是各种心脏病的严重表现和终末阶段,其发病率、病死率和再住院率均高。心脏再同步化治疗是目前治疗心脏失同步心力衰竭的重要方法,可改善心力衰竭患者的生活质量,降低病死率和减少心脏性猝死的发生,其治疗反应性的有无常与碎裂QRS波群的出现相关。碎裂QRS波群是心脏病患者心电图上出现的心室除极异常的一个指标,研究发现它与多种心脏疾病有关。现就碎裂QRS波群在心脏再同步化治疗患者中的研究认识发展及现状做一总结。

Fragmented QRS Complex in Cardiac Resynchronization Therapy

Heart failure is the most serious cardiovascular problem in the 21st century,which is the terminal stage of various heart diseases,and its incidence rate,mortality and rehospitalization rate are high.Cardiac resynchronization therapy is currently an important method for the treatment of cardiac non-synchrony heart failure,which can improve the quality of life of patients with heart failure,reduce the mortality and the occurrence of sudden cardiac death.The response of the treatment is inconstant,which is related to the occurrence of fragmented QRS complex.Fragmented QRS complex is an indicator of abnormal ventricular depolarization on the electrocardiogram of patients with heart disease and has been found to be associated with a variety of heart diseases.This paper reviews the development and current situation of the study on fragmented QRS complex in patients with cardiac resynchronization therapy.