一氧化碳中毒迟发性脑病的MRI表现

目的:研究一氧化碳(CO)中毒迟发性脑病的MRI特征.方法:回顾性分析32例CO中毒迟发性脑病患者的MRI和临床资料.结果:CO中毒迟发性脑病MRI表现可分为三型:①神经核团受累型;②脑白质受累型;③皮层受累型.MRI特征:苍白球为对称性的卵圆形长T1、长T2信号,皮层下白质为对称性的弥漫、模糊云雾状长T1、长T2信号,侧脑室周围、半卵圆中心白质亦为对称云絮状长T1、长T2信号,胼胝体常受累.MRI显示苍白球合并脑白质受累者及皮层受累者,临床表现较重.结论:CO中毒迟发性脑病MRI表现有一定特征性,且能反应其病理过程,并对CO中毒迟发性脑病的诊断和评价临床表现、预后均有意义.

MRI Manifestations of Delayed Encephalopathy after Carbon Monoxide Poisoning

Objective:To investigate the MRI features of delayed encephalopathy after carbon monoxide poisoning.Methods:MRI findings and clinical materials of 32 cases diagnosed as delayed encephalopathy after carbon monoxide poisoning were retrospectively studied.Results:On the bases of MRI findings,delayed encephalopathy after carbon monoxide poisoning were classified into three types:Type 1:showing neural nuclei involvement;Type 2:showing white matter involvement and Type 3:showing brain cortex involvement.Characteristic MRI signs demonstrated symmetrical oval long T1 and long T2 signal intensity foci in bilateral globus pallidus,and,symmetrical,diffuse,cloudy and blurred lesions of long T1 and long T2 signal intensity appeared in the subcortical white matters of the centrum semiovale and also those surrounding both lateral ventricles.Corpus callosum was often involved.The clinical manifestations were more serious in those cases that multiple involvements of the globus pallidus complicated with white matter and cortex impairment occurred.Conclusion:MRI findings of delayed encephalopathy after carbon monoxide poisoning were able to reflect not only the characteristic patho-logical courses of the disease,but also to provide important diagnostic information for the evaluation of clinical pictures and prediction of prognosis of the cases.