| HPLC 测定甲硝唑葡萄糖注射液中甲硝唑的含量 |
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| 引用本文： | 何继祥,母琼梅.HPLC 测定甲硝唑葡萄糖注射液中甲硝唑的含量[J].华西药学杂志,2001,16(2):128-128,131. |
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| 作者姓名： | 何继祥 母琼梅 |
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| 作者单位： | 1. 曲靖市药品检验所
2. 曲靖市医疗单位第二制剂室, |
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| 摘 要： | 目的采用HPLC测定甲硝唑葡萄糖注射液中甲硝唑含量。方法用ODS柱(3.9 mm×300 mm)，以甲醇-水(40∶60)为流动相，检测波长为310 nm。结果在25～125 μg*ml-1范围内，甲硝唑峰面积与浓度呈良好线性关系，r=0.9999，平均回收率为99.90%，RSD为0.43%(n=6)。结论该方法简便、准确可靠。
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| 关 键 词： | 甲硝唑葡萄糖注射液 甲硝唑 含量测定 高效液相色谱法 抗原虫药 |
| 文章编号： | 1006-0103(2001)02-0128-02 |
DETERMINATION OF METRONIDAZOLE IN METRONIDAZOLE AND GLUCOSE INJECTION BY HPLC |
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| HE Ji-xiang,MU Qiong-mei.DETERMINATION OF METRONIDAZOLE IN METRONIDAZOLE AND GLUCOSE INJECTION BY HPLC[J].West China Journal of Pharmaceutical Sciences,2001,16(2):128-128,131. |
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| Authors: | HE Ji-xiang MU Qiong-mei |
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| Abstract: | OBJECTIVE:To establish an HPLC for determination of metronidazole in the metronidazole and glucose injection. METHODS:The column was μbondapak ODS， the mobile phase consisted of methanol-water(40∶60)，the detective wavelength was 310 nm.RESULTS:The recovery of metronidazole was 99.90%,RSD was 0.43%(n=6).The linear range was 25～125 μg*ml-1(r=0.9999).CONCLUSION:The method was simple and accurate. |
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| Keywords: | HPLC Metronidazole Injection |
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