Enteral nutrition and infections: the role of human milk |
| |
| Affiliation: | 1. Neonatal Unit and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;2. Neonatal Immunology Laboratory, Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;3. Department of Internal Medicine and Therapeutics, University of Pavia, Italy;4. Neonatology and NICU, S. Anna Hospital, Torino, Italy;1. Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;2. Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;1. Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;2. Department of Obstetrics and Gynaecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;3. Neonatology and Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;4. Radiology and Neuroradiology Department, Children''s Hospital V. Buzzi, Milano, Italy |
| |
| Abstract: | Human milk (HM) is known as the best nutrition for newborns and support the optimal growth of infants, providing essential substances, nutrients, bioactive and immunologic constituents. HM also grants a favorable microbial colonization with attendant priming/maturation of the gut. The bioactive and immunologic elements of HM demonstrated to protect offspring against infection and inflammation and contribute to immune maturation. Some of these elements are being investigated in order to be used to ameliorate formula milk. A formula milk similar to breast milk may help neonatal gut to build a microbiota near to the one of the breast fed infants, improving the neonate's protection against pathogens.The aim of this review is to summarize the most significant bioactive constituents of HM that own natural anti-infectious properties and contribute to neonatal immune defense. |
| |
| Keywords: | Neonatal infection Human milk Bioactive constituents Enteral nutrition |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
