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Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP‐BEZ235, a dual PI3K/MTOR inhibitor,in regulating the PI3K/MTOR pathway in colorectal cancer
Authors:Areumnuri Kim  Jung‐Eun Lee  Seung‐Sook Lee  Cherin Kim  Sun‐Joo Lee  Won‐Suk Jang  Sunhoo Park
Affiliation:1. Laboratory of Experimental Pathology, Korea Institute of Radiological and Medical Science, , Seoul, Korea;2. Department of Pathology, Korea Institute of Radiological and Medical Science, , Seoul, Korea
Abstract:
Keywords:colorectal cancer  PI3K/MTOR  KRAS/PIK3CA mutation  BIM
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