对艾滋病合并肺结核患儿实施药学监护的探讨

目的 探讨临床药师对1例艾滋病合并肺结核患儿实施药学监护实践的经验与体会.方法 深入临床,发现实际存在或潜在的用药问题,协助医师调整治疗方案,对患儿进行健康用药教育,包括①抗结核“四联”方案可能引起尿色发红、消化道症状、肝功能损害、皮疹等;②抗病毒治疗时应防止阳光照射皮肤,避免烈性皂类;③定期监测血常规、血脂、乳酸、肝功能等.结果 治疗2d后,患儿抗巨细胞病毒抗体弱阳性,结核病治疗14 d出院;出院时肝功能ALT由入院时84 U/L降至43 U/L.临床药师充分发挥药学专长,提高了临床治疗效果.结论 临床药师参与临床药物治疗,可促进药物合理使用.

Experience of clinical pharmaceutical care for child with acquired immune deficiency syndrome complicated with pulmonary tuberculosis

Objective To discuss clinical experience and perspectives of pharnmcentical care for acquired immune deficiency syndrome complicated by pulmonary tuberculosis patients. Methods The actual orhidden prob- leIns of clinical drug use were detected by chnieal pharmacists during clinical practice, which helped physician adjust treatment program and conduct health education. Results Two days after treatment, cytomegalovirus antibodies was weakly positive. After treatment for 14 days, the tuberculsis was cured and the child discharged from hospital,and the level of alanine transarninase decreased from 84 U/L to 43 U/L. Clinical pharmacists improved clinical therapeutic ef- ficacy. Conclusion Clinical pharmacists can promote rational drug use by participating in clinical drug treatment.