急性脑梗死与血浆同型半胱氨酸的相关性分析

目的 观察急性脑梗死与血浆同型半胱氨酸(Hcy)的关系.方法 对102例脑梗死患者(脑梗死组)及113例体检健康者(对照组)进行血浆Hcy检测,比较2组血浆Hcy水平的差异,并分析其与脑梗死的关系.结果 脑梗死组患者中高Hcy血症45例(42.9％),血浆Hcy水平平均为(16.4±3.1) μmol/L,对照组高Hcy血症12例(9.8％),血浆Hcy水平平均为(10.0±1.8) μmol/L,2组比较差异有统计学意义(P＜0.01).结论 脑梗死患者血浆Hcy水平明显高于正常人,高Hcy血症可能是脑梗死的危险因素.

Analysis of relationship between acute cerebral infarction and plasma homocysteine

Objective To observe the relationship between acute cerebral infarction and plasma homocys- teine（Hcy）. Methods Serum homocysteien levels were tested in patients with cerebral infarction and the normal to analyze the relationship between hyperhomocysteinemia and cerebral infarction. Results The average level of serum homoeysteine in patients with the cerebral infarction was （ 16.4 ± 3.1 ） μmol/L, and the average level of serum ho- moeysteine in the normals was （ 10.0 ±1.8） μmol/L. There was a significant difference between two groups （P 〈 0.01 ）. Conclusions Patients with cerebral infarction have a higher level of serum homoeysteine than normal, so hyperhomocysteinemia may be one of the dangerous faetors of cerebral infarction. It is possible to reduce and delay the development of cerebral infarction by decreasing the level of serum homocysteine.