|
|||||
|
|
Treatment of bladder carcinoma with irradiation combined with misonidazole |
|
| Authors: | C Papavasiliou D Yiogarakis N Davillas L Seretakis J Pappas M Licourinas C Theodorou P Stathopoulos C Katsoyianni A Thanos |
| Institution: | Hellenic Urologic Cancer Cooperative Group, Participating Institutions: University of Athens, Departments of Radiology, Urology, Epidemiology and Clinical Therapeutics, State Hospital of Athens and Army Fund (NIMTS) Hospital of Athens, Greece |
| Abstract: | One hundred patients suffering from cancer of the bladder were treated by external beam irradiation, 400 cGy twice a week to a total dose of 4800 cGy. One half of the patients were randomized to receive the electron affinic sensitizer agent, misonidazole, at a dose of 1 gr/m2 and a total dose of 12 gr/m2. There was no statistically significant difference in tumor responses and in recurrence--free survival time between the patients who received irradiation and misonidazole as compared to those who received irradiation and placebos. |
| Keywords: | Cancer of the bladder External radiotherapy Electron affinic radiosensitizers Fractionation of irradiation |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |