| 异丙酚与咪唑安定对体外循环期脑氧供需平衡的影响 |
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| 引用本文： | 陈爱武 李李. 异丙酚与咪唑安定对体外循环期脑氧供需平衡的影响[J]. 湖南医科大学学报, 2000, 25(1): 65-67 |
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| 作者姓名： | 陈爱武 李李 |
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| 摘 要： | ３０例瓣膜置换术病人随机分为对照组,异丙酚组和咪唑安定组,观察体外循环期颈静脉血氧饱和度,动脉,颈内静脉血氧含量差,脑氧摄取率的变化。结果表明;复温时Ⅱ,Ⅲ组ＳｊＯ２显著高于Ⅰ组,Ｄａ－ｖＯ２及ＣＥＯ２显著低于组,且复温时ＳｊＯ２与ＣＰＢ前相比差异无显著性。提示异丙酚与咪唑安均能防止ＣＰＢ时脑氧供需失衡。
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| 关 键 词： | 体外循环 异丙酚 咪唑安定 脑 供氧 |
Effect of propofol and midazolam on cerebral oxygen supply and demand imbalance during cardiopulmonary bypass] |
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| A W Chen,L Li,Y T Chang. Effect of propofol and midazolam on cerebral oxygen supply and demand imbalance during cardiopulmonary bypass][J]. Bulletin of Hunan Medical University, 2000, 25(1): 65-67 |
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| Authors: | A W Chen L Li Y T Chang |
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| Affiliation: | Department of Anesthesiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011. |
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| Abstract: | Thirty patients undergoing heart valve replacement were divided randomly into three groups (n = 10): control group, propofol group and midazolam group. Jugular bulb blood oxygen saturation (SjO2), arterialvenous oxygen content difference (Da-vO2) and cerebral oxygen extraction rate(CEO2) were measured at various periods of cardiopulmonary bypass (CPB). The results showed: SjO2 decreased significantly, Da-vO2 and CEO2 increased markedly during rewarming period in control group; but in propofol group and midazolam group, SjO2, CEO2 and Da-vO2 did not decline significantly compared with baseline. It is suggested that administering propofol or midazolam is helpful in avoiding cerebral oxygen supply and demand imbalance during CPB. |
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