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| 中药板蓝根中高级不饱和脂肪酸的分离鉴定及免疫活性成分的研究 | |
| 引用本文： | 秦箐,贺海平,陈鸣. 中药板蓝根中高级不饱和脂肪酸的分离鉴定及免疫活性成分的研究[J]. 中国现代医学杂志, 2001, 11(1): 15-16 |
| 作者姓名： | 秦箐 贺海平 陈鸣 |
| 作者单位： | 1. 广西医科大学化学教研室 2. 广西肿瘤研究所生化室 3. 丹麦皇家药学院药物化学系 4. 丹麦国家大学医院微生物部 |
| 基金项目： | 中国 -丹麦科技合作协议Danida资助项目!(项目编号AM 9:3)，广西教育厅资助项目 |
| 摘 要： | 从十字花科植物菘蓝（Isatis tinctorial L.)的根中首次人鉴定出一组含有三种分子的高级不饱和脂肪酸，命名为板蓝根组酸，并发现其对人多形核细胞（PMN）氧化作用及化学发光具有激活作用，而其邻近流分则具有抑制活性。 |
| 关 键 词： | 板蓝根 板蓝根组酸 人多形核细胞 化学发光 |
ISOLATION OF HIGHER UNSATURATED FATTY ACIDS AND STUDY OF IMMUNOLOGICALLY COMPETENT CONSTITUENTS FROM ISATIS TINCTORIA L |
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| Qin Jing Chemical Research Center of Guangxi Medical University,Guangxi. ISOLATION OF HIGHER UNSATURATED FATTY ACIDS AND STUDY OF IMMUNOLOGICALLY COMPETENT CONSTITUENTS FROM ISATIS TINCTORIA L[J]. China Journal of Modern Medicine, 2001, 11(1): 15-16 | |
| Authors: | Qin Jing Chemical Research Center of Guangxi Medical University Guangxi |
| Affiliation: | Qin Jing Chemical Research Center of Guangxi Medical University,Guangxi 530021 |
| Abstract: | To make isolation of a fraction and its subfractions from'Banlangen',root of Isatis tinctoria L.,and study their immunocompetence.Methods:Afraction 3 and its subfractions were isolated from'Banlangen'with dry-column flash chromato-graphy.It was tested that the effect of those fractions on chemiluminescence(CL) reaction of human polymorphonuclear cells(PMN).Results:A group of higher unsaturated fatty acids that contain three different moleuculse were isolated and elucidated from'Banlan-gen'for the first time and was named Banlangen-acids.A two-way immunocompetence was found form fraction 3 and its subfractins.Conclusion:There are some anti-inflamation components in fraction 3 and its subfractions from'Banlangen'.Banlangen-acids take an important role in it. |
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