急性脑梗死患者脑白质病变因素风险评估

目的探讨脑白质病变对急性脑梗死患者预后的影响。方法选择驻马店市中心医院收治的282例急性脑梗死患者,根据MRI检查结果分为脑白质病变组(115例)和无脑白质病变组(167例),对2组临床资料(性别、年龄、糖尿病、高血压、房颤、高血脂)情况进行统计,同时对全部患者随访90d,评价患者的预后情况。结果脑白质病变组和无脑白质病变组男女比例及平均年龄差异无统计学意义(P0.05)。而脑白质病变组糖尿病、高血压、房颤、高血脂的发生率及预后不良率、病死率显著高于无脑白质病变组(P0.01)。结论急性脑梗死患者若在影像学检查中发现脑白质病变,需对相关危险因素进行积极干预,可有效改善预后,降低病死率。

Risk assessment of white matter lesions on patients with acute cerebral infarction

Objective To explore the effect of brain white matter lesions on prognosis of patients with acute cerebral infarction.Methods Two hundred and eighty-two patients with acute cerebral infarction in the Central Hospital of Zhumadian were divided into brain white matter lesions group (115 patients) and non-brain white matter lesions group (167 patients).The clinical data (sex ratio,age,diabetes,hypertension,atrial fibrillation,hyperlipidemia) of the two groups were analyzed and compared,and all the patients were followed up for 90 days,the prognosis of all the patients were analyzed.Results There was no significant difference in the proportion of men and women and the average age between the patients in brain white matter lesions group and non-brain white matter lesions group (P ＞0.05).The incidence of diabetes,hypertension,atrial fibrillation and hyperlipidemia in the patients with white matter lesions was significantly higher than that in the patients without brain white matter lesions.The rate of poor prognosis and mortality in brain white matter lesions group was significantly higher than that in non-brain white matter lesions group (P＜0.01).Conclusion If the brain white matter lesions are detected in the patients with acute cerebral infarction,it is necessary to actively intervene the related risk factors,so as to effectively improve the prognosis and reduce the mortality.