男性2型糖尿病患者勃起功能障碍与抑郁症共病情况的探讨

目的 探讨男性2型糖尿病患者中勃起功能障碍与抑郁症共病情况。 方法 收集丽水市第二人民医院2015年11月—2018年11月收治的156例男性糖尿病勃起功能障碍(DMED)患者进行研究，根据抑郁自评量表的测评结果，将患者分为A组(DMED伴抑郁，105例)和B组(DMED不伴抑郁，51例)。计算DMED与抑郁症的共病率；比较2组患者的基线指标、血糖控制指标、性激素指标和血脂生化指标差异，采用Pearson相关性分析评判SDS量表评分与这些指标的相关性,并进行logistic回归分析。 结果 156例男性T2DM患者中，合并抑郁症者105例，共病率为67.31%。A组患者的年龄明显高于B组，T2DM病程明显较B组更长，FPG、FIns和HbA1c高于B组，TT水平低于B组，LH、FSH水平高于B组，差异具有统计学意义(均P＜0.05)。Pearson分析提示，SDS量表评分与年龄、T2DM病程、FPG、Fins、HbA1c、LH、FSH均呈正相关，与TT水平呈负相关(均P＜0.05)。Logistic回归分析显示，年龄、T2DM病程和TT水平是DMED与抑郁共病的独立危险因素(均P＜0.05)。 结论 男性T2DM患者中，DMED与抑郁症存在共病情况，年龄大、病程长、睾酮水平低下可能是两者共病的独立危险因素。 

The discussion on comorbidity of erectile dysfunction and depression in male patients with type 2 diabetes mellitus

Objective To investigate the comorbidity of diabetes mellitus erectile dysfunction and depression in male patients with type 2 diabetes mellitus. Methods One hundred and fifty-six male DMED patients in our hospital from November 2015 to November to 2018 were enrolled, who were divided into group A (DMED with depression,105 cases) and group B (DMED without depression,51 cases) according to the results of Self-rating depression scale (SDS). The co-morbidity of DMED and depression was calculated, and the differences of baseline index, blood sugar control index, sex hormone index and lipid biochemical index between the two groups were compared. Pearson correlation analysis was used to evaluate the correlation between SDS scale score and these indexes, and Logistic regression analysis was carried out. Results Among 156 male patients with T2DM, 105 had depression, with a total incidence of 67.31%. The age of group A was significantly higher than that of group B, the duration of T2DM was significantly longer than that of group B, FPG, FIns and HbA1c were higher than that of group B, TT was lower than that of group B, LH and FSH were higher than that of group B, the difference was statistically significant (all P<0.05). Pearson analysis showed that SDS score was positively correlated with age, course of T2DM, FPG, Fins, HbA1c, LH and FSH, and negatively correlated with TT level (all P<0.05). Logistic regression analysis showed that age, duration of T2DM and TT level were independent risk factors for comorbidity of DMED and depression (all P<0.05). Conclusions In male T2DM patients, DMED has a comorbid condition with depression. Old age, long course of T2DM and low TT may be the independent risk factors for the comorbidity.