彩色多普勒超声对乳腺与甲状腺疾病诊断的相关性分析

目的 探讨彩色多普勒超声技术对乳腺疾病合并甲状腺疾病的诊断价值。 方法 2016年1月—2018年12月采用区组法按接诊顺序分别纳入女性乳腺恶性肿瘤患者(乳腺恶性肿瘤组)、乳腺良性病变患者(乳腺良性病变组)及乳腺健康者(乳腺健康组)每组各50例,共150例。3组均经甲状腺二维及彩色多普勒超声检查。比较3组的低回声甲状腺结节检出率，甲状腺体积，左右双侧甲状腺血流动力学指标甲状腺上动脉、下动脉的甲状腺动脉内径(D)、收缩期峰值血流速度(SPV)、平均血流速度(MV)、舒张期血流速度(DV)、加速时间(AT)、减速时间(DT)]。 结果 与乳腺健康组比较，乳腺恶性肿瘤组、乳腺良性病变组检出低回声甲状腺结节的比例更高(均P＜0.05)。与乳腺健康组比较，乳腺恶性肿瘤组、乳腺良性病变组的甲状腺体积均明显增大(均P<0.05)。与其他2组比较，乳腺恶性肿瘤组的甲状腺体积增大更明显(均P<0.05)。与乳腺健康组比较，乳腺恶性肿瘤组的甲状腺血流动力学指标D、SPV、DV值升高，AT、DT值降低(均P<0.05)；乳腺良性病变组的SPV值升高，AT、DT值降低(均P<0.05)。与乳腺良性病变组比较，乳腺恶性肿瘤组的SPV值升高及AT、DT值降低的更显著(均P<0.05)。 结论 乳腺疾病和甲状腺疾病有一定关联性、相互影响，临床借助超声影像手段可实现对乳腺疾病合并甲状腺疾病的筛查。 

Role of color Doppler ultrasound in studying the correlation between breast and thyroid diseases

Objective To discuss the diagnostic value of color Doppler ultrasonography in breast diseases with thyroid diseases. Methods From January 2016 to December 2018, total 150 female patients with breast malignant tumors (breast malignant tumors group), benign breast lesions (breast benign lesions group) and healthy breast patients (breast health group) were enrolled into this study using block method according to the order of admission, with 50 cases in each group. All patients in the three groups were examined by two-dimensional and color Doppler ultrasonography to diagnose thyroid diseases. The detection rate of hypoechoic thyroid nodules, the volume of thyroid gland and the mean of hemodynamic indexes of both sides of thyroid gland were investigated. The measured indexes included the diameter of thyroid artery (D), peak systolic blood flow velocity (SPV), mean blood flow velocity (MV), diastolic blood flow velocity (DV), acceleration time (AT) and deceleration time (DT). Results Compared with the healthy breast group, the proportion of hypoechoic thyroid nodules was higher in malignant breast cancer group and benign breast lesion group (P<0.05). Compared with healthy breast group, thyroid volume in malignant breast cancer group and benign breast lesion group increased significantly (all P<0.05). Compared with the other two groups, the thyroid volume increased more significantly in breast cancer group (P<0.05). Compared with the healthy breast group, the thyroid hemodynamic indexes D, SPV and DV increased, while AT and DT decreased in the malignant breast group (all P<0.05); SPV increased in the benign breast lesion group, while AT and DT decreased (all P<0.05). Compared with benign breast lesions, SPV and AT and DT in malignant breast tumors were higher than those in benign breast lesions (all P<0.05). Conclusion Breast diseases and thyroid diseases are related and interacted. Clinical screening and diagnosis of breast diseases combined with thyroid diseases by means of ultrasound imaging has practical significance for evaluating the complications and prognosis of breast diseases.