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河西走廊中段地区上消化道疾病患者幽门螺杆菌感染状况
引用本文:梁晓萍,张丽秀,张多强,张建芳,张娟,罗晓慧,罗荣,陈根,韩俭. 河西走廊中段地区上消化道疾病患者幽门螺杆菌感染状况[J]. 中国病原生物学杂志, 2011, 0(4)
作者姓名:梁晓萍  张丽秀  张多强  张建芳  张娟  罗晓慧  罗荣  陈根  韩俭
作者单位:兰州大学病原生物学研究所;兰州大学第二临床医学院;张掖市人民医院普外科;张掖市人民医院病理科;
基金项目:甘肃省自然科学基金项目(No.0803RJZA073); 兰州大学“国家大学生创新性实验计划”项目(No.091073053)
摘    要:
目的探讨河西走廊中段地区上消化道疾病患者幽门螺杆菌(Hp)感染状况,分析Hp感染与上消化道疾病的关系。方法收集上消化道疾病患者胃粘膜石蜡标本及病理资料,采用W-S银染和革兰染色检查患者组织中Hp感染状况,分析Hp感染与性别、年龄及病理特征之间的关系。结果受检标本Hp阳性率为81.3%(178/219)。浅表性胃炎组、癌前病变组和胃癌组Hp阳性率依次为60.7%、77.4%和85.6%。浅表性胃炎组Hp感染率与胃癌组比较差异有统计学意义(P<0.05);61岁以上组Hp感染率与60岁以下各组比较差异有统计学意义(P<0.05);有淋巴结转移胃癌组Hp感染率与无转移组比较差异有统计学意义(P<0.05);Hp感染率在不同性别、不同胃癌组织病理类型、癌组织大小及浸润深度间差异无统计学意义(P>0.05)。结论在河西走廊中段地区胃癌的发生及其淋巴结转移与Hp感染有关。Hp感染率随年龄增大呈上升趋势。

关 键 词:幽门螺杆菌  河西走廊中段  胃癌  

The prevalence of Helicobacter pylori infection among patients with an upper gastrointestinal tract disease in the middle of the Hexi Corridor
LIANG Xiao-ping,ZHANG Li-xiu,ZHANG Duo-qiang,ZHANG Jian-fang,ZHANG Juan,LUO Xiao-hui,LUO Rong,CHEN Gen,HAN Jian. The prevalence of Helicobacter pylori infection among patients with an upper gastrointestinal tract disease in the middle of the Hexi Corridor[J]. Journal of Pathogen Biology, 2011, 0(4)
Authors:LIANG Xiao-ping  ZHANG Li-xiu  ZHANG Duo-qiang  ZHANG Jian-fang  ZHANG Juan  LUO Xiao-hui  LUO Rong  CHEN Gen  HAN Jian
Affiliation:LIANG Xiao-ping1,ZHANG Li-xiu2,ZHANG Duo-qiang3,ZHANG Jian-fang2,ZHANG Juan2,LUO Xiao-hui2,LUO Rong4,CHEN Gen1,HAN Jian1 (1.Institute of Pathogenic Biology of Lanzhou University,Lanzhou 730000,China,2.The Second Clinical Medical College of Lanzhou University,3.Department of General Surgery,People's Hospital of Zhangye Municipality,4.Pathology Department,People's Hospital of Zhangye Municipality)
Abstract:
Objective To determine the prevalence of Helicobacter pylori(Hp) infection among patients with upper gastrointestinal tract disease in the middle of the Hexi Corridor and analyze the relationship between Hp infection and upper gastrointestinal tract disease.Methods Samples of gastric mucosa were embedded in paraffin and pathologic data were collected from patients.Warthin-Starry silver staining and Gram staining were used to detect Hp infection in the samples.The relationship between Hp infection and sex,ag...
Keywords:Helicobacter pylori  the middle of the Hexi Corridor  gastric cancer  
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