Some Ultrastructural Aspects of Lymph-Node Cells and Hepatocytes in Papular Acrodermatitis of Childhood

Ultrastructural examination of the inguinal lymph-nodes of six patients with papular acrodermatitis of childhood with hepatitis B antigenemia showed the presence of several Langerhans cells and, in three cases, the presence of some mononucleate cells, the cytoplasm of which contained groups of 20-50 spherical particles, approximately 150 A in diameter and with an electron-dense core. In the hepatocytes of two of these patients we observed spherical particles ranging in size between 150 A and 220 A, having an electron-lucent core and scattered throughout areas limited by a membrane.