刺络放血治疗成人斯蒂尔病临床观察

目的：观察刺络放血治疗成人斯蒂尔病的临床疗效。方法：选取成人斯蒂尔病患者164例。采取随机的方法分为两组各82例。两组均使用甲氨蝶呤作为基础用药，对照组加用尼关舒利胶囊治疗；治疗组采取刺络放血治疗方法。记录关节情况，实验室检查，毒副作用等观察指标。结果：治疗组明显进步51例，进步21例，改善6例，无效4例，总有效率为95．12％（95％CI=90．46％-99．78％）；对照组明显进步34例，进步24例，改善11例，无效13例，总有效率为84．15％（95％CI=76．25％-92．05％）；两组综合疗效比较（u=2．7571，P=0．0077），差异有显著性意义；治疗后治疗组体温、关节积分、实验室指标等较对照组有明显改善；毒副作用较对照组明显降低。结论：刺络放血合甲氨蝶呤治疗成人斯蒂尔病疗效优于尼美舒利合甲氨蝶呤，其收益为OR=0．27（95％CI=0．08～0．87），NNT=9（95％CI=4．9～91．0）。

Clinical Observation of Venesection and Bloodletting on Adult Still Disease

Objective: To observe the clinical effect of venesection and blood letting on adult Still disease.Methods: 164 cases with adult Still disease were selected and divided into two groups randomly,and 82 cases in each group.On the basis of the treatment with methopterin,control group was treated with nimesulide,and treatment group was done with venesection and blood letting.Articulus information,laboratory examination,and side effects were observed and recorded.Results: In treatment group 51 cases were excellen...