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| 大理白族地区乙型肝炎流行模式与基因分型初探 | |
| 引用本文： | 李美兰,易寿生,忽胜和,王磊,施春华. 大理白族地区乙型肝炎流行模式与基因分型初探[J]. 中华医院感染学杂志, 2012, 22(13): 2746-2747 |
| 作者姓名： | 李美兰 易寿生 忽胜和 王磊 施春华 |
| 作者单位： | 1. 大理学院附属医院检验科,云南大理,671000 2. 大理州疾病预防控制中心,云南大理,671000 3. 云南省剑川县疾病预防控制中心,云南剑川县,671500 |
| 基金项目： | 云南省教育厅科学研究基金项目(08y0331) |
| 摘 要： | 目的 掌握白族人群乙型肝炎的流行情况及流行模式,并对其基因分型进行初步探讨.方法 在流行病调查的基础上用实时荧光定量法进行DNA载量测定及基因分型.结果 425例乙型肝炎标志物结果A组(大三阳)阳性率为24.7％ ;B组(小三阳)阳性率为34.4％；50例扩增例数基因分型结果B型23例,占46.0％；C型20例,占40.0％；D型5例,占10.0％；C型/D型混合感染2例,占4.0％.结论 该地区乙型肝炎流行模式以小三阳为主；基因分布以B型居多,C型次之. |
| 关 键 词： | 白族地区 乙型肝炎病毒 流行模式 基因分型 |
Prevalence modes and genotyping of hepatitis B in Dali minority areas |
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| LI Mei-lan , YI Shou-sheng , HU Sheng-he , WANG Lei , SHI Chun-hua. Prevalence modes and genotyping of hepatitis B in Dali minority areas[J]. Chinese Journal of Nosocomiology, 2012, 22(13): 2746-2747 | |
| Authors: | LI Mei-lan YI Shou-sheng HU Sheng-he WANG Lei SHI Chun-hua |
| Affiliation: | (The Affiliated Hospital of Dali College,Dali,Yunnan 671000,China) |
| Abstract: | OBJECTIVE To study the present condition of prevalence modes and genotyping of hepatitis B epidemic in Dali minority areas.METHODS The DNA loading and genotyping were determined through real-time fluorescence quantitative method on the basis of epidemic investigation.RESULTS Of 425 cases of the markers of hepatitis B,the positive rate was 24.7% in group A(Da sanyang),34.4% in group B(Xiao sanyang).The results of genotyping of 50 amplified cases were: 23 cases of type-B(46.0%),20 cases of type-C(40.0%),5 cases of type-D(10.0%),and 2 cases of type-C/D(4.0%).CONCLUSION The major prevalence mode of hepatitis B in this area is Xiao sanyang,and the most prevalent genotype is type-B,and type-C. |
| Keywords: | Minority area Hepatitis B virus Prevalence modes Genotyping |
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