Pathomorphism of endemic goiter

Pathomorphism of goiter developing against the background of goiter prevention in the Bukovina endemic area was studied. Subdivision of goiter into endemic and sporadic lost its significance due to the stabilization and levelling of the goiter morbidity. The true (simple or benign) goiter is characterized by an euthyroid course, predominant affection of adult women and domination of the nodular variants. A goiter node is a hyperplastic structural-functional gland unit--the thyron. The leading role in the goiter etiology belongs to endogenous deficiency of thyroid hormones, local factors are significant in the goiter pathogenesis.