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Cell microvesicles during experimental endotoxemia
Authors:L. D. Zubairova  D. M. Zubairov  I. A. Andrushko  G. Yu. Svintenok  I. G. Mustafin
Affiliation:(1) Department of Biochemistry, Kazan State Medical University, Kazan
Abstract:
The dynamics of microvesicle formation in arterial blood in generalized Schwartzman phenomenon was studied. Successive (with 24-h interval) intravenous injections of endotoxin to rabbits in a dose of 1 mg/kg and 3 mg/kg caused an increase in the content of microvesicles in the blood, some of them containing ecto-5′-nucleotidase. Biphasic changes in arterial blood clotting time and erythrocyte hemolysis were observed. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 517–520, November, 2006
Keywords:endotoxin  microvesicles  rabbit  blood clotting  hemostasis
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