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强心冲剂治疗慢性充血性心力衰竭的临床疗效观察分析
引用本文:孙兰军,王保和,赵英强,张景江,武重阳,郑偕扣,王瑞华. 强心冲剂治疗慢性充血性心力衰竭的临床疗效观察分析[J]. 天津中医学院学报, 2006, 0(3)
作者姓名:孙兰军  王保和  赵英强  张景江  武重阳  郑偕扣  王瑞华
作者单位:天津中医药大学第二附属医院,天津中医药大学第二附属医院,天津中医药大学第二附属医院,天津市北辰中医院,天津中医药大学,天津中医药大学第二附属医院,天津中医药大学第二附属医院
基金项目:国家中医药管理局科研基金课题(02-03LP17)。
摘    要:
[目的]通过临床试验、随访分析评价其治疗效果。[方法]采用随机、多中心、阳性药对照的原则,进行临床评价,随访研究分析强心冲剂的治疗效果。[结果]治疗组心功能、中医症状、Lee氏心力衰竭计分显效率分别为43.3%、43.3%、35.0%,总有效率为73.3%、83.3%、71.7%,对照组显效率分别为46.7%、35.0%、38.3%,总有效率为80.0%、81.7%、和80.0%。组间比较均P>0.05。选取部分病例随访,继续服药8周后其疗效优于服药4周。停药6个月后,治疗组、对照组、西药组的再住院率分别为3.2%、6.8%、6.67%,心血管大事件发生率分别为6.4%、6.8%、10.0%。[结论]强心冲剂的“益气温阳,活血利水”改善心衰症状,降低心衰患者的再住院率、心血管大事件的发生率,疗效确切。

关 键 词:慢性充血性心力衰竭  强心冲剂  临床疗效  观察分析

Clinical Effect Observation and Analysis of Qiangxin Composition on Treating Chronic Congestive Heart Failure
SUN Lan-jun,WANG Bao-he,ZHAO Ying-qiang,et al. Clinical Effect Observation and Analysis of Qiangxin Composition on Treating Chronic Congestive Heart Failure[J]. Journal of Tianjin College of Traditional Chinese Medicine, 2006, 0(3)
Authors:SUN Lan-jun  WANG Bao-he  ZHAO Ying-qiang  et al
Abstract:
[Objective] To evaluation the curative effect of Qiangxin composition by using clinical experiment and follow-up analysis study. [Methods] To carry out clinical evaluation and follow-up analysis study on the curative effect of Qiangxin composition according to randomly,multicentre and control of masccline medicine principle. [Results] The excellence rate of treatment group were individually 43.3%,43.3%,35% and total effective rate of treatment group were individually 73.3%,83.3%,71.7%,on the heart function,TCM symptoms and Lee scores of heart failure. The excellence rate of control group were individually 46.7%,35%,38.3% and total effective rate of treatment group were individually 80%,81.7%,80% on the heart function,TCM symptoms and Lee scores of heart failure. There weren't obviously differentiation between the treatment group and control group. To carry out follow-up study on the partly cases. The curative effect in eight weeks had an advantage than that in four weeks. The rehospitalization rate were individually 3.2%,6.8%,6.67% and the incidence rate of important heart vessel event were individually 6.4%,6.8%,10% in the treatment group,control group and western medicine group. [Conclusion] The Qiangxin composition have a definite curative effect on improving symptoms of heart failure,decreasing rehospitalization rate and the incidence rate of important heart vessel event in the heart failure patients.
Keywords:chronic congestive heart failure  Qiangxin composition  clinical effect  observation and analysis
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