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Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor.
Authors:E J Kuipers  E Vellenga  J T de Wolf  B P Hazenberg
Affiliation:Department of Internal Medicine, University Hospital, Groningen, The Netherlands.
Abstract:
We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days. This case and 2 others reported in the literature emphasize the need for further research into the possible role of GM-CSF in the treatment of drug induced agranulocytosis.
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