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| 肺结核患者血清纤维指标检测的临床意义 | |
| 引用本文： | 宋志丽,康卫国. 肺结核患者血清纤维指标检测的临床意义[J]. 临床军医杂志, 2006, 34(5): 544-545 |
| 作者姓名： | 宋志丽 康卫国 |
| 作者单位： | 1. 解放军沈阳军区大连疗养院,辽宁,大连,116013 2. 解放军第148医院,山东,淄博,255300 |
| 摘 要： | 目的探讨肺结核患者血清纤维指标变化的临床意义。方法采用放免法检测82例肺结核病人及40例健康体检者的血清透明质酸(HA)、层粘连蛋白(LN)、Ⅲ型前胶原(PCⅢ)、Ⅳ型胶原(CⅣ)含量。结果肺结核患者血清Ⅲ型前胶原和血清Ⅳ型胶原非常显著升高(P<0.01);血清层粘连蛋白显著升高(P<0.05)。结论检测血清纤维指标对肺结核患者肺纤维化的动态观察和早期诊断具有重要意义。 |
| 关 键 词： | 肺结核 肺纤维化 血清纤维指标 |
| 文章编号： | 1671-3826（2006）05-0544-02 |
| 收稿时间： | 2006-08-09 |
| 修稿时间： | 2006-08-09 |
The Clinical Significance to Detect Serum Fibrosis Markers for Pulmonary Tuberculosis Patients |
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| Song Zhi-li,Kang Wei-guo. The Clinical Significance to Detect Serum Fibrosis Markers for Pulmonary Tuberculosis Patients[J]. Clinical Journal of Medical Officer, 2006, 34(5): 544-545 | |
| Authors: | Song Zhi-li Kang Wei-guo |
| Affiliation: | 1. PLA Dalian Sanatorium of Shenyang Militraty Region, Dalian 116013,China;2. PLA 148th Hospital, Zibo 255300, China |
| Abstract: | Objective To investigate the clinical significance of changes of serum fibrosis marker in pulmonary tuberculosis patients.Methods The serum hyaluronic acid,laminin,procollagen Ⅲ and collagen Ⅳ was detected for 82 cases of patients with pulmonary tuberculosis and 40 cases of control group.Results The serum level of laminin(109.26±23.42 ng/ml)in pulmonary tuberculosis patients was markedly higher than control group(98.80±17.92 μg/L).The serum level of procollagen Ⅲ(175.2±84.83 μg/L) in pulmonary tuberculosis patients obviously higher than control group(99.13±25.92 μg/L).The serum level of collagen Ⅳ(75.57±37.11 μg/L) in pulmonary tuberculosis patients was markedly higher than control group(51.01±17.86 μg/L.Conclusion It is a important significance to detect these serum fibrosis markers for early diagnosis of pulmonary fibrosis with pulmonary tuberculosis patients and its development observation. |
| Keywords: | pulmonary tuberculosis pulmonary fibrosis serum fibrosis marker |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |