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Pulmonary embolism after arterial chemoembolization for hepatocellular carcinoma: An autopsy case report
Authors:Keiichi Hatamaru  Shunjiro Azuma  Takuji Akamatsu  Takeshi Seta  Shunji Urai  Yoshito Uenoyama  Yukitaka Yamashita  Kazuo Ono  
Affiliation:Keiichi Hatamaru, Shunjiro Azuma, Takuji Akamatsu, Takeshi Seta, Shunji Urai, Yoshito Uenoyama, Yukitaka Yamashita, Department of Gastroenterology and Hepatology, Japan Red Cross Society Wakayama Medical Center, Wakayama 640-8558, JapanKazuo Ono, Department of Pathology, Japan Red Cross Society Wakayama Medical Center, Wakayama 640-8558, Japan
Abstract:We report an extremely rare case of pulmonary lipiodol embolism with acute respiratory distress syndrome(ARDS) after transcatheter arterial chemoembolization(TACE) for hepatocellular carcinoma(HCC). A 77-yearold man who was diagnosed with a huge HCC wasadmitted for TACE. Immediately after the procedure, this patient experienced severe dyspnea. We suspected that his symptoms were associated with a pulmonary lipiodol embolism after TACE, and we began intensive treatment. However, his condition did not improve, and he died on the following day. A subsequent autopsy revealed that the cause of death was ARDS due to pulmonary lipiodol embolism. No cases have been previously reported for which an autopsy was performed to explain the most probable mechanism of pulmonary lipiodol embolism; thus, ours is the first report for such a rare case.
Keywords:Hepatocellular carcinoma   Transcatheter arterial chemoembolization   Pulmonary lipiodol embolism   Acute respiratory distress syndrome   Autopsy
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