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| MMPs/TIMPs与风湿性心脏病房颤患者心房结构重构的研究进展 | |
| 引用本文： | 薛邦德,张兴华,周华富. MMPs/TIMPs与风湿性心脏病房颤患者心房结构重构的研究进展[J]. 中国现代手术学杂志, 2007, 11(6): 475-477 |
| 作者姓名： | 薛邦德 张兴华 周华富 |
| 作者单位： | 广西医科大学第一附属医院心胸外科,南宁,530021 |
| 摘 要： | MMP/TIMP的平衡失调参与了房颤者心房结构重构特别是心房纤维化的发生和发展。以此作为靶点可以为风湿性心瓣膜病房颤的治疗提供新的思路。本文就MMPs、TIMPs的结构、生物学特性、功能、调控以及其在房颤治疗方面的进展作一综述。 |
| 关 键 词： | 基质金属蛋白酶类 金属蛋白酶类组织抑制剂 心房颤动 风湿性心脏病 |
| 文章编号： | 1009-2188（2007）06-0475-03 |
| 收稿时间： | 2007-09-10 |
| 修稿时间： | 2007-10-16 |
Advances of the Influence of MMPs/TIMPs on Atrial Structural Remodeling in Patients with Atrial Fibrillation Caused by Rheumatic Heart Diseases |
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| XUE Bang-de,ZHANG Xin-hua,ZHOU Hua-fu. Advances of the Influence of MMPs/TIMPs on Atrial Structural Remodeling in Patients with Atrial Fibrillation Caused by Rheumatic Heart Diseases[J]. Chinese Journal of Modern Operative Surgery, 2007, 11(6): 475-477 | |
| Authors: | XUE Bang-de ZHANG Xin-hua ZHOU Hua-fu |
| Abstract: | The of MMPs/TIMPs disbalance participates in the atrial structural remodeling in patients with atrial fibrillation,especially in atrial fibrosis cases,which may provide a new therapeutic approach for atrial fibrillation in rheumatic valvular disease.The structure, bionomics,function,regulation and its relative therapeutic progress of MMPs/TIMPs are reviewed in this article. |
| Keywords: | matrix metalloproteinase tissue inhibitor of metalloproteinases atrial fibrillation rheumatic heart disease |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |