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检测唾液IgM抗-HAV诊断甲型肝炎的研究
引用本文:汪义和,张燕琴,刘如星,邵芯仪,刘宝根. 检测唾液IgM抗-HAV诊断甲型肝炎的研究[J]. 中华流行病学杂志, 1992, 13(1): 9-11
作者姓名:汪义和  张燕琴  刘如星  邵芯仪  刘宝根
作者单位:浙江省杭州市卫生防疫站 310006;杭州市第六人民医院
摘    要:本文采用检测唾液IgM抗-HAV来诊断甲型病毒性肝炎(甲肝)进行了研究。结果表明,IgM抗-HAV能可靠地在血清学证实的58例急性甲肝和9例甲乙混合感染的患者唾液中检出,而不能在非甲肝患者其中包括84例急性乙肝和30例非甲非乙肝及10例健康人唾液中检出。证明采用唾液标本来诊断甲肝是特异的。唾液比血清更易获得,这就为今后甲肝的诊断和流行病学调查提供了更有利的条件。

关 键 词:唾液诊断 甲型肝炎 IgM抗-HAV
收稿时间:1990-11-22
修稿时间:1991-03-05

Study on Diagnosis of Hepatitis A by Testing Salivary IgM Anti-HAV
Wang Yihe. Study on Diagnosis of Hepatitis A by Testing Salivary IgM Anti-HAV[J]. Chinese Journal of Epidemiology, 1992, 13(1): 9-11
Authors:Wang Yihe
Affiliation:Hangzhou Health and Anti-epidemic Station, Zhejiang Province.
Abstract:The use of salivary samples to diagnose acute hepatitis A was investigated. Result indicated that IgM anti-HAV can be reliably detected in saliva of 58 cases with acute hepatitis A and 9 cases with mixed infection of hepatitis A and B. It is not present in saliva of individuals without recent hepatitis A including 84 cases with acute hepatitis B, 30 cases of hepatitis non A non B and 10 healthy individuals. It was suggested that use of salivary samples to diagnose hepatitis A was specific. It's concluded that saliva is a convenient and satisfactory alternative to serum for the clinical diagnosis and epidemiological investigation of hepatitis A infection.
Keywords:Salivary diagnosis  IgM anti-HAV  Hepatitis A
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