山东省莒南县流行性出血热病人血清分型及宿主动物的调查研究

本文报道了山东省莒南县流行性出血热(EHF)病人血清分型及宿主动物的调查研究结果。用血凝抑制试验(HI)对262例EHF病人进行血清分型,结果230例为家鼠型病人(87.78%),29例为野鼠型(11.07%),未定型3例(1.15%)。检测该地11种动物的肺组织或血清,从7种动物的肺中检测出EHF病毒抗原,主要是黑线姬鼠、大仓鼠、褐家鼠、猪、羊、家兔和黄鼬等,前4种还同时查出血清抗体。进一步证实鼠类是主要传染源。猪的感染可能与发病有关,但尚待进一步证实。

Study on the Serological Typing of Patients with Epidemic Hemorrhagic Fever (EHF)and Host Animals in Junan County, Shangdong prouince

Using hemagglutination inhibition test (HI), we confirmed that Junan County is an endemic area of both EHF of R. norvegicus and A. agrarius, which indicated that the main host animals were R. norvegicus and A. agrarius in the area. Remarkable difference was shown between the infectious rates of pigs from the endemic area and that of pigs from the nonendemic area, which suggested that pigs could play certain roles in the transmission of EHF. We also proved that the main transmission mode of EHF virus in rats was horizontal transmission, and vertical transmission in rats also existed.