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A low n-6 to n-3 polyunsaturated fatty acid ratio diet improves hyperinsulinaemia by restoring insulin clearance in obese youth
Authors:Domenico Tricò MD  Alfonso Galderisi MD  Michelle A. Van Name MD  Sonia Caprio MD  Stephanie Samuels MD  Zhongyao Li RD  Brittany T. Galuppo BS  Mary Savoye RD  Andrea Mari PhD  Ariel E. Feldstein MD  Nicola Santoro MD
Affiliation:1. Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa;2. Hopital Necker-Enfants Malades, Paris, France;3. Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA;4. Institute of Neuroscience, National Research Council, Padua, Italy;5. Department of Pediatrics, University of California San Diego, San Diego, California, USA;6. Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA

Department of Medicine and Health Sciences, “V.Tiberio” University of Molise, Campobasso, Italy

Abstract:
Keywords:adolescents  β-cell function  dietary lipids  fatty liver disease  glucose metabolism  insulin clearance  insulin metabolism  insulin resistance  insulin secretion  liver  obesity
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