| 盐酸恩丹西酮葡萄糖注射液稳定性研究 |
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| 引用本文： | 刘丽萍,谢永忠. 盐酸恩丹西酮葡萄糖注射液稳定性研究[J]. 中国药房, 2004, 15(2): 87-89 |
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| 作者姓名： | 刘丽萍 谢永忠 |
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| 作者单位： | 1. 安徽医科大学附属第一医院药剂科,合肥市,230022
2. 黄山市人民医院药剂科,黄山市,245000 |
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| 摘 要： | 目的 :研究盐酸恩丹西酮葡萄糖注射液的稳定性。方法 :以高效液相色谱法测定盐酸恩丹西酮及其有关物质的含量 ,分别用强光照射法、加速试验法和室温留样观察法对盐酸恩丹西酮葡萄糖注射液进行稳定性试验。结果 :除强光照射条件下本品含量略有下降外 ,加速试验和室温留样观察各项指标均符合质量标准的规定。结论 :本品在避光、密闭的贮存条件下性质稳定 ,室温下贮存期可定为2年。
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| 关 键 词： | 盐酸恩丹西酮葡萄糖注射液 稳定性 高效液相色谱法 |
| 文章编号： | 1001-0408(2004)02-0087-03 |
| 修稿时间： | 2003-10-22 |
Study on the Stability of Ondansetron Hydrochloride Glucose Injection |
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| LIU Liping. Study on the Stability of Ondansetron Hydrochloride Glucose Injection[J]. China Pharmacy, 2004, 15(2): 87-89 |
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| Authors: | LIU Liping |
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| Abstract: | OBJECTIVE:To study the stability of Ondansetron hydrochloride glucose injection(OHGI).METHODS:The contents of Ondansetron hydrochloride and its related substances were determined with HPLC.The stability of the samples were tested by high-light exposure,accelerating experiment and room temperature storage.RESULTS:After exposure to high light,the content in OHGI slightly decreased but on other experiments,it was rather stable.CONCLUSION:This injection should be kept away from high light and may be stored for2years at room temperature. |
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| Keywords: | Ondansetron hydrochloride glucose injection stability HPLC |
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