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茶藤中生物碱成分的研究
引用本文:王世平,李玲,徐冉,吴君.茶藤中生物碱成分的研究[J].中国药房,2012(19):1766-1768.
作者姓名:王世平  李玲  徐冉  吴君
作者单位:贵阳医学院机能实验室;贵州大学生命科学学院
基金项目:国家自然科学基金资助项目(30471592)
摘    要:目的:研究茶藤的生物碱类成分。方法:运用多种层析方法对茶藤进行分离与纯化,并根据理化性质和波谱数据对其结构进行鉴定。结果:从茶藤中分离得到4个化合物,分别为斯砍定(Scandine)、柳叶水甘草碱(Tabersonine)、11-羟基柳叶水甘草碱(11-Hydroxytabersonine)、19S-长春里宁(19S-Vindolinine)。4个化合物均为首次从该植物中分离得到。结论:本试验结果可在一定程度上为茶藤的活性研究奠定基础。

关 键 词:山橙属  茶藤  生物碱  分离  鉴定

Study on the Alkaloids from Melodinus magnificus
WANG Shi-ping,LI Ling,WU Jun.Study on the Alkaloids from Melodinus magnificus[J].China Pharmacy,2012(19):1766-1768.
Authors:WANG Shi-ping  LI Ling  WU Jun
Institution:(Functional Laboratory,Guiyang Medical College,Guiyang 550004,China) XU Ran(College of Life Sciences,Guizhou University,Guiyang 550002,China)
Abstract:OBJECTIVE:To study the alkaloids from Melodinus magnificus.METHODS:Multiply column chromatography techniques were applied for the isolation and purification of M.magnificus.The structures were identified with their physicochemical properties and spectral data.RESULTS:4 compounds were isolated and identified from M.magnificus,such as scandine,tabersonine,11-hydroxytabersonine,19S-vindolinine.All compounds were isolated from the species for the first time.CONCLUSION:The results of trial lay a foundation for the study of the activity of M.magnificus to some extent.
Keywords:Apocynaceae Melodinus  Melodinus magnificus  Alkaloids  Isolation  Identification
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