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Amplatz血栓消融器治疗急性深静脉血栓的实验研究
引用本文:沈志勇,张纪蔚,张皓,张柏根.Amplatz血栓消融器治疗急性深静脉血栓的实验研究[J].上海交通大学学报(医学版),2004,24(10):826-829.
作者姓名:沈志勇  张纪蔚  张皓  张柏根
作者单位:上海第二医科大学仁济医院普外科,上海200001
摘    要:目的 评价Amplatz血栓消融器(ATD)治疗急性深静脉血栓形成动物模型的近期疗效。方法 30条实验犬麻醉后,经右侧股静脉插入Fogarty球囊导管,完全阻断肾下下腔静脉,诱导深静脉血栓形成,用ATD经右侧股静脉进行旋切去栓治疗,在第7、14、30d后再次行静脉造影,观察下腔静脉的通畅度。结果 ATD旋切去栓治疗急性深静脉血栓形成的技术操作成功率为100%,近期的通畅率为100%,血栓形成复发率14.8l%。无明显的血管壁损伤和肺动脉栓塞的病理学现象。结论 ATD治疗急性深静脉血栓安全、快速、有效,无明显的并发症。

关 键 词:治疗  急性  ATD  Amplatz血栓消融器  深静脉血栓形成  股静脉  下腔静脉  技术操作  诱导  成功率
文章编号:0258-5898(2004)10-0826-04
修稿时间:2003年12月29

Experiment study of mechanical thrombectomy by Amplatz thrombectomy device for acute deep venous thrombosis
SHEN Zhi-yong,ZHANG Ji-wei,ZHANG Hao,ZHANG Bai-gen.Experiment study of mechanical thrombectomy by Amplatz thrombectomy device for acute deep venous thrombosis[J].Journal of Shanghai Jiaotong University:Medical Science,2004,24(10):826-829.
Authors:SHEN Zhi-yong  ZHANG Ji-wei  ZHANG Hao  ZHANG Bai-gen
Abstract:Objective To evaluate the short-term effect of mechanical thrombectomy by Amplatz thrombectomy de-v ice ( ATD) for acute deep venous thrombosis (DVT). Methods Canine models with DVT were developed by completely occluding the infra-renal inferior vena cave ( IVC ) with a Fogarty balloon catheter via the right femoral vein. Mechanical thrombectomy by ATD was given and patency of infra-renal IVC was restored in the canines on 7, 14 d and 30 d. Results The success of mechanical thrombectomy by ATD in animal models with DVT was 100%. The short-term patency was 100% and no significant pulmonary embolism or vascular endothelial injury was found. Conclusion Mechanical ihrombectomy by ATD for acute DVT is safe, rapid and effective.
Keywords:deep venous thrombosis  Amplatz thrombeetomy device  Fogarty balloon eatheter
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