临床检验生化指标在病毒性肝病患者诊断中的应用与分析

目的探讨临床检验生化指标在病毒性肝病患者诊断中的应用价值。方法选择300例病毒性肝病患者作为观察组,同期300例健康体检者作为对照组。两组均开展生化指标检验。比较两组生化指标水平及肝功能指标阳性率。结果观察组总胆红素(25.13±5.13)μmol/L、谷丙转氨酶(96.32±10.89)U/L、淋巴细胞计数(2.56±0.52)×10^9/L高于对照组的(14.53±3.44)μmol/L、(29.24±4.77)U/L、(1.17±0.04)×10^9/L,白球比(1.06±0.12)、白蛋白(38.25±4.23)g/L、白细胞计数(5.02±0.65)×10^9/L、血小板计数(111.23±21.42)×10^9/L、中性粒细胞计数(1.25±0.13)×10^9/L低于对照组的(2.23±0.35)、(48.25±6.29)g/L、(7.23±1.29)×10^9/L、(178.96±30.28)×10^9/L、(3.89±0.97)×10^9/L,差异具有统计学意义(P<0.05)。观察组谷丙转氨酶、总胆红素、胆碱酯酶阳性率分别为85.00%、92.00%、89.67%,均高于对照组的9.00%、12.00%、7.33%,差异具有统计学意义(P<0.05)。结论与健康人群相比,病毒性肝病患者生化指标异常情况明显,多项生化指标能够直接反映患者病情,开展临床生化检验,对病毒性肝病患者的诊断及预后判断具有重要作用。

Application and analysis of clinical laboratory biochemical indicators in the diagnosis of patients with viral liver disease

Objective To discuss the practical value of clinical laboratory biochemical indicators in the diagnosis of patients with viral liver disease.Methods There were 300 patients with viral liver disease as the observation group,300 cases of healthy subjects as the control group.Biochemical indicators were tested in both groups.The levels of biochemical indicators and the positive rate of liver function indicators were compared between the two groups.Results The total bilirubin(25.13±5.13)μmol/L,alanine aminotransferase(96.32±10.89)U/L,lymphocyte count(2.56±0.52)×10^9/L in the observation group were higher than those in the control group(14.53±3.44)μmol/L,(29.24±4.77)U/L,(1.17±0.04)×10^9/L,and globulin ratio(1.06±0.12),albumin(38.25±4.23)g/L,white blood cell count(5.02±0.65)×10^9/L,platelet count(111.23±21.42)×10^9/L and neutrophil count(1.25±0.13)×10^9/L were lower than those in the control group(2.23±0.35),(48.25±6.29)g/L,(7.23±1.29)×10^9/L,(178.96±30.28)×10^9/L and(3.89±0.97)×10^9/L],and the difference was statistically significant(P<0.05).The positive rates of alanine aminotransferase,total bilirubin,and cholinesterase in the observation group were 85.00%,92.00%,and 89.67%,respectively,which were all higher than 9.00%,12.00%,and 7.33%of the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with healthy people,the abnormality of biochemical indicators in patients with viral liver disease is obvious.Many biochemical indicators can directly reflect the patient’s condition.The development of clinical biochemical tests plays an important role in the diagnosis and prognosis judgement of patients with viral liver disease.