首页 | 本学科首页   官方微博 | 高级检索  
     

急性心肌梗死患者溶栓后血浆中脑钠素浓度变化的研究
引用本文:赵雅琳,蒋宝国. 急性心肌梗死患者溶栓后血浆中脑钠素浓度变化的研究[J]. 中华老年心脑血管病杂志, 2006, 8(3): 168-170
作者姓名:赵雅琳  蒋宝国
作者单位:1. 沈阳医学院奉天医院,辽宁,沈阳,110024
2. 中国医科大学附属第四医院,辽宁,沈阳,110032
摘    要:目的研究血中脑钠素(BNP)水平与急性心肌梗死溶栓后左心室射血分数(LVEF)和心肌缺血程度的关系。方法将198例顺序入选的急性心肌梗死行链激酶静脉溶栓治疗的患者分为溶栓成功组(105例)和溶栓未成功组(93例),检测所有患者的血BNP水平及测定LVEF,比较溶栓成功组与溶栓未成功组LVEF>40%和LVEF≤40%的BNP水平。结果溶栓成功组BNP水平明显低于溶栓未成功组的BNP水平(725.4±169.8)ng/L(P<0.05),溶栓成功组和未成功组中LVEF>40%患者的BNP水平[(107.7±46.5)ng/L,(488.5±88.9)ng/L]明显低于LVEF≤40%患者的BNP水平[(515.5±121.2)ng/L,(856.7±129.5)ng/L,P<0.01]。结论急性心肌梗死患者血中BNP水平与LVEF和心肌缺血程度有关。

关 键 词:心肌梗塞  利钠肽,脑  血栓溶解疗法  危险因素
文章编号:1009-0126(2006)03-0168-03
收稿时间:2005-07-08
修稿时间:2005-07-08

Plasma levels of brain natriuretic peptide in acute myocardial infarction patients after thrombolysis
ZHAO Ya-lin,JIANG Bao-guo. Plasma levels of brain natriuretic peptide in acute myocardial infarction patients after thrombolysis[J]. Chinese Journal of Geriatric Cardiovascular and Cerebrovascular Diseases, 2006, 8(3): 168-170
Authors:ZHAO Ya-lin  JIANG Bao-guo
Abstract:Objective To investigate the relationship between plasma levels of brain natriuretic peptide(BNP) and left ventricular ejection fraction(LVEF) and degree of myocardial ischemia in patients with acute myocardial infarction(AMI) after thrombolytic therapy.Methods 198 AMI patients treated with intravenous thrombolysis were randomly divided into two groups.BNP concentration of coronary repatency group was compared with that of myocardial ischemia group,and that of LVEF>40% with that of LVEF≤40% patients respectively in two groups.Results Plasma BNP concentration in coronary repatency group was significantly lower than that in myocardial ischemia group[(327.9±85.4) vs(725.4±169.8) ng/L,P<0.05].In coronary repatency group,plasma BNP concentration was(107.7±46.5) ng/L in LVEF>40% patients and(515.5±121.2) ng/L in LVEF≤40% patients.In myocardial ischemia group,plasma BNP concentration in LVEF>40% patients was significantly lower than that in LVEF≤40% patients [(488.5±88.9) ng/L vs(856.7±129.5) ng/L](P<0.01).Conclusion Plasma BNP concentration is related to LVEF and the degree of myocardial ischemia after thrombolytic therapy for acute myocardial infarction.
Keywords:myocardial infarction  natriuretic peptide  brain  thrombolytic therapy  risk factors
本文献已被 CNKI 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号