MR全肝灌注成像在直肠癌肝转移中应用的初步探讨

目的：探讨MR全肝灌注检查对直肠癌肝转移的临床应用价值。方法：选择46例直肠癌患者（16例肝转移，30例无肝转移）行MR全肝灌注扫描，采用三维容积内插序列（3D-VIBE），对比剂按注射流率4ml／s，扫描时平静呼吸，连续扫描90S，每3S进行一次全肝采集。在工作站上获取腹腔干水平腹主动脉、门静脉主干、肝实质和脾脏的时间一信号强度曲线（TIC），计算肝实质的相对肝动脉灌注量（HAP）、相对门静脉灌注量（HPP）及肝动脉灌注指数（HPI），并对有或无肝转移组的上述指标进行统计分析。结果：肝转移组HPI（平均0．387）高于无肝转移组（平均0．285），而肝转移组相对HPP值（平均0．967）低于无肝转移组（平均为1．332），其中HPI和HPP在两组间差异有统计学意义（P〈0．05），而肝转移组的相对HAP值（平均0．565）高于无肝转移组（平均0．535），但在两组间差异无统计学意义（P〉0．05）。结论：MR全肝灌注检查技术可分析肝内血流灌注的改变，对预测直肠癌肝转移有重要潜在应用价值。

Preliminary Study of MR Whole Liver Perfusion Weighted Imaging in the Detection of Liver Metastases of Rectal Carcinoma

Objective:To investigate the clinical value of MR whole liver perfusion weighted imaging (PWI) in the depiction of liver metastases in patients with rectal carcinoma.Methods:Forty-six patients with rectal carcinoma were divided into 2 groups,[16 patients with liver metastases (MG) and 30 patients without (NMG)],all of them underwent MR whole liver PWI,3D volume interpolated breath-hold sequence (3D VIBE) was used,which were performed every 3s continuously for 90s during the injection of contrast medium at t...