腹腔镜手术联合米非司酮治疗子宫内膜异位症的临床研究

目的探讨腹腔镜手术与米非司酮联合治疗子宫内膜异位症的疗效。方法选择2012年3月~2013年10月在我院就诊的80例子宫内膜异位症患者,随机分为单纯腹腔镜手术对照组(A组,n=40)和腹腔镜手术联合米非司酮治疗观察组(B组,n=40),B组采用手术联合米非司酮治疗。对两组疗效结果和术后复发及受孕情况等指标结果进行比较。结果随访结果发现,A组总有效率为72.5%,B组有效率为95.0%,B组疗效明显优于A组(P<0.05),B组的复发率较A组明显降低,且受孕率明显提高,差异均有统计学意义(P<0.05)。结论腹腔镜手术联合米非司酮的疗效优于单纯腹腔镜手术,值得临床推广。

The clinical efficacy of laparoscopic surgery combined with mifepristone in treatment of endometriosis

Objective To observe the clinical efficacy of laparoscopic surgery combined with mifepristone in treatment of endometriosis （EM）. Methods Eighty cases of patients with EM admitted to our hospital from Mar 2012 to Oct 2013 were randomly divided into the control group which treated with laparoscopy operation（A group, n=40） and the observa- tion group which treated by operation combined with mifepristone （B group, n=40）. The clinical efficacy and adverse events were compared between the groups. Results The effective rate of single group A was 72.5%, while it was 95.0% in group B. The recurrence rate of group B was significantly superior than group A, and group B obviously improved the conception rate, had statistical difference （P 〈 0.05）. Conclusion The laparoscopic surgery combined with mifepris- tone in treatment of EM has good effect and worth clinical promotion.