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| 活血汤对阿霉素肾硬化大鼠病理改变的影响 | |
| 引用本文： | 李清初,王太华,周庚寅.活血汤对阿霉素肾硬化大鼠病理改变的影响[J].华夏医学,2006,19(1):28-30. |
| 作者姓名： | 李清初 王太华 周庚寅 |
| 作者单位： | 1. 桂林医学院,广西,桂林,541001 2. 泰山医学院,山东,泰安,271000 3. 山东大学医学院,山东,济南,250012 |
| 摘 要： | 目的:探讨活血汤对阿霉素(ADR)肾硬化大鼠病理改变的影响。方法:复制阿霉素肾硬化模型并用活血汤来治疗。观测药物干预前后蛋白尿、尿糖、白蛋白(ALB)、尿素氮(BUN)、肌酐(C r)、血脂(TG、CHO)的变化。观察肾脏组织中肾小球硬化和其他病理损伤程度。结果:药物治疗组的蛋白尿、肾功能和病理改变较肾硬化组有明显的改善。结论:活血汤能改善大鼠的临床症状、肾功能,并且活血汤能明显减轻肾小球硬化、肾小管损伤,最终延缓肾小球硬化。 |
| 关 键 词： | 肾小球硬化 活血化淤汤 病理改变 |
| 文章编号： | 1008-2409(2006)01-0028-03 |
| 修稿时间： | 2005年5月20日 |
Effect of Huoxuehuayu tang on pathology chang of Adriamycin-induced glomerulosclerosis in rats |
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| LI Qing-chu,WANG Tai-hua,ZHOU Geng-yin.Effect of Huoxuehuayu tang on pathology chang of Adriamycin-induced glomerulosclerosis in rats[J].Acta Medicinae Sinica,2006,19(1):28-30. | |
| Authors: | LI Qing-chu WANG Tai-hua ZHOU Geng-yin |
| Abstract: | Objective: To investigate the effect of huoxue tang on the pathology chang of kidney of Adriamycin-induced glomerulosclerosis in rats.Methods: The models of Adriamycin-induced glomerulosclerosis in rats were made and treated with huoxue tang.Then albuminuria,urine glucose,albumin,creatinine,urea nitrogen,cholesterol,triglycerin before cured and at the end of the study were detected.The pathology chang in kidney of rats were analyzed.Results: The albuminuria,renal function and pathology chang of kidney in huoxue tang group ameliorated.Conclusion: It is suggested that Huoxue tang can reduce proteinuria and retard the development of glomerulosclerosis.Huoxue tang is effective to cure Adriamycin-induced glomerulosclerosis in rats. |
| Keywords: | glomerulosclerosis huoxue tang pathology change |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |