| 西安市城市居民食管癌的病因研究:烟酒因素的作用 |
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| 引用本文： | 韩成龙,李良寿,万志恒. 西安市城市居民食管癌的病因研究:烟酒因素的作用[J]. 中华流行病学杂志, 1988, 9(1): 12-15 |
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| 作者姓名： | 韩成龙 李良寿 万志恒 |
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| 作者单位： | 中国人民解放军第四军医大学流行病学教研室 |
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| 摘 要： | 本文报道了1984年10月~1985年10月西安市城市居民138例食管癌的病例对照研究。结果表明,吸烟为食管癌发病的危险因素,ORM-H为4.12(95% CI为1.57~6.54)。OR与吸烟量、吸烟年限有显著剂量效应关系。吸烟作为食管癌的可能致病因子其潜隐期为37.19年。饮酒与食管癌的联系不显著(χ2=1.03,P﹥0.05)。作者认为吸烟单独或与其它因素共同作用下可能参与食管的癌变过程。
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| 关 键 词： | 食管癌 病例对照研究 烟酒因素 |
A Causative Factors Study of Esophageal Cancer among City Inhabitants in Xian: The Role of Smoking & Drinking |
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| Han Chenglong. A Causative Factors Study of Esophageal Cancer among City Inhabitants in Xian: The Role of Smoking & Drinking[J]. Chinese Journal of Epidemiology, 1988, 9(1): 12-15 |
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| Authors: | Han Chenglong |
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| Affiliation: | Department of Epidemiology, The Fourth Military Medical College, Xian |
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| Abstract: | A case-control study of 138 cases of esophageal cancer (EC) and 138 non-cancer matched controls and 5607 (male, 3739, female, 1868) normal population controls was reported. Both case group and control group consisted of city inhabintants in Xian in north-west China. It was found that smoking was a risk factor of EC.The OR for smoker was 4.12 (95% CI was 1.57~6.54). The significant dose-response relationship between OR and cigarette consumption or duration of smoking was found, while there was no significant association between drinking and EC (P>0.05). It was suggested that smoking, solely or combining with some other factors, may involve in the carcinogenesis of the esophagus. |
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| Keywords: | Esophageal cancer Casecontrol study Smoking and drinking |
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